inca,
Hi,
I do not know the age of this person but some years ago there was a clinical diagnosis for stuff like this called (if memory serves correctly): Reaction to Adult Life. It was a sort of grad bag diagnosis for anxiety and depression cases where there were no classical patterns of thoughts and feelings (or precipitating events) that allowed a more specific differential diagnosis. My sense of some of these cases was that they were more what used to be called "existential crises".
If you can get her permission for Reiki then I would say focusing work at Tanden woul dbe a place to start.
Cheers,
RC