Dear harmony,
My humble intuitive take on that is that she was releasing / grounding pent/stuck negative energy as opposed to toxins. Two different things although they can have connecting tendrils of commonality between granted.
A fine Reiki session as you describe sets the stage for the toxin release but manifests hours or days/weeks later if the recipient works with (allows) it.
Negative energy release is a more realtime event i believe.
Does she have any aside symtoms of what might be ascribed to RLS?
Namaste,
Michael